Publications since 1986
De Robertis E.M. (2022). The impact of Developmental Biology in the last 100 years. Dev. Biol., 489, 118-121. PMID: 35716718 https://doi.org/10.1016/j.ydbio.2022.06.007
De Robertis, E.M. and Tejeda-Muñoz N. (2022). Evo-Devo of Urbilateria and its larval forms. Dev. Biol., 487, 10-20. PMID: 35443190 https://doi.org/10.1016/j.ydbio.2022.04.003
Tejeda-Muñoz, N. and De Robertis E.M. (2022). Lysosomes are required for early dorsal signaling in the Xenopus embryo. Proc. Natl. Acad. Sci. U.S.A., 119, e2201008119. PMID: 35446621 doi: 1073/pnas.2201008119
Tejeda-Muñoz, N. and De Robertis E.M. (2022). Wnt, GSK3 and Macropinocytosis. Subcell. Biochem. 98, 169-187. https://doi.org/10.1007/978-3-030-94004-1_9
Tejeda-Muñoz, N., Morselli, M., Moriyama, Y., Sheladiya, P. Pellegrini, M., and De Robertis, E.M. (2022). Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis. iScience 25, 104123. https://doi.org/10.1016/j.isci.2022.104123
Tejeda-Muñoz, N., Morselli, M., Moriyama, Y., Sheladiya, P. Pellegrini, M., and De Robertis, E.M. (2022). Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis. iScience 25, 104123. https://doi.org/10.1016/j.isci.2022.104123
De Robertis, E.M. and Tejeda-Muñoz N. (2022). Signaling components in dorsal-ventral patterning and the organizer in Xenopus. In: Xenopus, from basic biology to disease models in the genomic era. S. A. Moody and A. Fainsod, Eds. Boca Raton: CRC Press, pp. 43-50. ISBN 978-0367505271
Albrecht, L.V, Tejeda-Muñoz, N. and De Robertis, E.M. (2021). Cell biology of canonical Wnt signaling. Annu. Rev. Cell Dev. Biol., 37, 369-389 https://doi.org/10.1146/annurev-cellbio-120319-023657 PMID: 34196570
De Robertis, E.M. and Tejeda-Muñoz, N. (2021). Signaling Components in Dorsal-Ventral Patterning and the Organizer in Xenopue. In: Xenopus, from basic biology to disease models in the genomic era. S. A. Moody and A. Fainsod, Eds. Taylor and Francis CRC Press, in press.
Zhang, F., Zhu, X., Wang, P., He, Q. Huang, H., Zheng, T. Li, Y., Jia, H., Xu, L., Zhao, H., Colozza, G., Tao, Q.*, De Robertis, E.M*. and Ding, Y.* (2021). The Cytokine FAM3B/PANDER is an FGFR Ligand that Promotes Posterior Development in Xenopus. Proc. Natl. Acad. Sci. U.S.A., in press. *Corresponding authors.
De Robertis, E.M. and Gurdon, J.B. (2021). A brief history of Xenopus in biology. Cold Spring Harb. Protoc. https://doi:1101/pdb.top.107615
Albrecht, L.V., Tejeda-Muñoz N and De Robertis E.M. (2020). Protocol for probing regulated lysosomal activity and function in living cells. STAR Protocols 1, 1001132 doi: http://doi.org/10.1016/j.xpro.2020.100132 PMCID: PMC7757114 PMID: 33377026
Niehrs, C. (2021). Lessons from the Organizer – an interview with Edward M. (Eddy) De Robertis. Int. J. Dev. Biol. 65, 111-122. https://doi.org/10.1387/ijdb.190298cn
De Robertis, E.M., Tejeda-Muñoz, N. and Albrecht, L. (2020). Wnt signaling as a regulator of cellular endocytosis and protein stability. Pontif. Acad. Sci. Acta 25, 227-238. http://www.casinapioiv.va/content/dam/accademia/pdf/pas_acta25.pdf
Colozza, G., Jami-Alahmadi, Y., Dsouza, A., Tejeda-Muñoz, N., Albrecht, L.V., Sosa, E., Wohlschlegel, J.A. and De Robertis E.M. (2020). Wnt-inducible Lrp6-APEX2 interactive proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway. Sci. Rep. 10, 21555 doi: https://doi.org/10.1038/s41598-020-78019-5 PMID: 33299006
Albrecht, L.V., Tejeda-Muñoz, N., Bui, M.H., Cicchetto, A., Azzolin, L., Colozza, G., Schmid, E., Piccolo, S., Christofk, H.R. and De Robertis, E. M. (2020). GSK3 inhibits macropinocytosis and lysosomal activity through the Wnt destruction complex machinery. Cell Reports 32, 107973 doi: https://doi.org/10.1016/j.celrep.2020.107973
Colozza, G. and De Robertis E.M. (2020) Dact-4 is a Xenopus laevis Spemann organizer gene related to the Dapper/Frodo antagonist of beta-catenin family of proteins. Gene Expr. Patterns 38, 119153 doi: https://doi.org/10.1016/j.gep.2020.119153 PMID: 33186756
Sosa, E.A., Moriyama, Y., Ding, Y., Tejeda-Munoz, N., Colozza G. and De Robertis, E. (2019). Transcriptome analysis of regeneration during Xenopus laevis experimental twinning. Int. J. Dev. Biol. 63, 301-309.
Tejeda-Munoz, N., Albrecht, L.V., Bui, M.H. and De Robertis, E.M. (2019). Wnt canonical pathway activates macropinocytosis and lysosomal degradation of extracellular proteins. Proc. Natl. Acad.Sci. 116, 10402-10411.
Albrecht, L.V., Bui, M.H. and De Robertis, E.M. (2019). Canonical Wnt is inhibited by targeting one carbon metabolism through methrotrexate of methionine deprivation. Proc. Natl. Acad. Sci. USA 116, 2987-2995.
Ding, Y., Colozza, G., Sosa, E.A., Moriyama, Y., Rundle, S., Salwinski, L. and De Robertis, E.M. (2018). Bighead is a novel Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis. Proc. Natl. Acad. Sci. USA 115, E9135-E9144.
De Robertis, E.M. (2018). Regulation of protein degradation by Wnt signaling. Pontif. Acad. Sci. Scripta Varia 137, 177-186.
De Robertis, E.M. and Sanchez Sorondo, M., Eds. (2018). Cell Biology and Genetics. Pontificiae Academiae Scientarum Scripta Varia vol. 137, Libreria Editrice Vaticana, Rome, 330 pp. http://www.casinapioiv.va/content/dam/accademia/pdf/sv137/sv137pas.pdf
Albrecht, L., Ploper, D., Tejeda-Munoz, N and De Robertis, E.M. (2018). Arginine methylation is required for canonical Wnt signaling and endolysosomal trafficking. Proc. Natl. Acad. Sci. USA, 115. E5317-E5325.
Moriyama, Y. and De Robertis, E.M. (2018). Twinning: Embryonic regeneration by relocalization of the Spemann organizer in Xenopus. Proc. Natl. Acad. Sci. USA, 115, E4815-E4822.
Kirsch, N., Chang, L.S., Koch, S., Glinka, A., Dolde, C., Colozza, G., Benitez, M.D.J., De Robertis, E.M. and Niehrs, C. (2017). Angiopoietin-like 4 is a Wnt signaling antagonist that promotes LRP6 turnover. Dev. Cell 43, 71-82. http://www.sciencedirect.com/science/article/pii/S1534580717307347
De Robertis, E.M. (2017). New Knowledge on the Causes of Human Birth Defects: Impact on Society. Pontif. Acad. Sci. Acta 24. https://www.youtube.com/watch?v=-eBb7rkNmMs
Ding, Y., Ploper, D., Sosa, E.A., Colozza, G., Moriyama, Y., Benitez, M.D.J., Zhang, K., Merkurjev, D. and De Robertis, E.M. (2017). Spemann organizer transcriptome induction by early b-Catenin, Wnt, Nodal and Siamois signals in Xenopus laevis. Proc. Natl. Acad. Sci. USA 114, E3081-E3090. http://www.pnas.org/content/early/2017/03/22/1700766114.short?rss=1
De Robertis, E.M. (2016). The role of gene loss in animal evolution from an ancestral genetic tool-kit.. Pontif. Acad. Sci. Acta 23, http://www.pas.va/content/accademia/en/publications/acta/acta23/derobertis.html. Self Presentation
De Robertis, E.M. and Moriyama, Y. (2016). The chordin morphogenetic pathway. Curr. Top. Dev. Biol., Biol. 116, 231-245.
De Robertis, E.M. (2016). A short history of bone and embryonic induction. In: Induction of Bone Formation in Primates: the Transforming Growth Factor-β3. U. Ripamonti, Ed., CRC Press, pp. 9-12.
Publications 2011-2015
Demagny, H. and De Robertis, E.M. (2015). Point Mutations in the tumor suppressor Smad4/DPC4 enhance its phosphorylation by GSK3 and reversibly inactivate TGF-β signaling. Mol. Cell. Oncol. 3:1, doi:10.1080/2372556.2015.1025181.
De Robertis, E.M. and Ploper, D. (2015). Sperm motility requires Wnt/GSK3 stabilization of proteins. Dev. Cell 35, 401-402.
Blum, M., De Robertis, E.M., Wallingford, J.B. and Niehrs, C. (2015). Morpholinos: Anti-Sense and Sensibility. Dev. Cell 35, 145-149.
Bier, E. and De Robertis, E.M. (2015). BMP gradients: a paradigm for morphogen-mediated developmental patterning. Science 348, 1443 and aaa5838.
Kim, H., Vick, P., Hedtke, J., Ploper, D. and De Robertis, E.M. (2015). Wnt signaling translocares Lys48-linked polyubiquitinated proteins to the lysosomal pathway. Cell Reports 11, 1151-1159.
Ploper, D. and De Robertis, E.M. (2015). The MITF family of transcription factors: role in endolysosomal biogenesis, Wnt signaling and oncogenesis. Pharmacol. Res. 99, 36-43.
Demagny, H. and De Robertis, E.M. (2015). Smad4/DPC4: a Barrier against Tumor Progression driven by RTK/Ras/ERK and Wnt/GSK3 signaling. Mol. Cell. Oncol. doi:10.4161/23723556.2014.989133.
Ploper, D., Taelman, V.F., Robert, L., Perez, B., Titz, B.,Chen, H.W., Graeber, T.G., von Euw, E., Ribas, A. and De Robertis, E.M. (2015). MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells. Proc. Natl. Acad.Sci. 112, E420-E429.
De Robertis, E.M. (2014). Deciphering Complexity in Biology: Induction of Embryonic Cell Differentiation by Morphogen Gradients. Pontif. Acad. Sci. Acta 22.
De Robertis, E.M. (2014). Lessons from a great developmental biologist. Differentiation 88, 3-8.
De Robertis, E.M. and Niehrs, C. (2014). Herbert Steinbeisser: a life with the Xenopus embryo. Int. J. Dev. Biol. 58, 299-302.
De Robertis, E. M. (2014). Yoshiki Sasai 1962-2014. Cell 158, 1233-1235. See also Dev. Cell 30, 509-511.
Demagny, H., Araki, T. and De Robertis, E.M. (2014). The tumor suppressor Smad4/DCP4 is at the crossroads of Wnt, FGF and TGF-β signaling. Cell Reports 9, 1-13.
Colozza, G. and De Robertis, E.M. (2014). Maternal syntabulin is required for dorsal axis formation and is a germ plasm component in Xenopus. Differentiation, 10.1016/j.diff.2014.03.002.
Plouhinec, J.L., Zakin, L., Moriyama, Y. and De Robertis, E.M. (2013). Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo. Proc. Natl. Acad. Sci. U.S.A. 110, 20372-20379.
De Robertis, E.M. and Colozza, G. (2013). Development: Scaling to size by protease inhibition. Curr. Biol. 23, R652-R654.
Dobrowolski, R., Vick, P., Ploper, D., Gumper, I., Snitkin, H., Sabatini, D.D. and De Robertis, E.M. (2012). Presenilin deficiency or lysosomal inhibition enhance Wnt signaling through relocalization of GSK3 to the late endosomal compartment. Cell Reports 2, 1316-1328.
Dobrowolski, R. and De Robertis, E.M. (2012). Endocytic control of growth factor signaling: multivesicular bodies as signaling organelles. Nat. Rev. Mol. Cell Biol. 13, 53-60.
Eivers, E., Demagny, H., Choi, R.H. and De Robertis, E.M. (2011). Phosphorylation of Mad controls competition between Wingless and BMP signaling. Science Signaling 4, ra68.
Plouhinec, J.L., Zakin, L. and De Robertis, E.M. (2011). Systems control of BMP morphogen flow in vertebrate embryos. Curr. Opin. Genet. Dev. 21, 1-8.
De Robertis, E.M. (2011). Evo-Devo: the merging of evolutionary and developmental biology. In: The Scientific Legacy of the 20th Century, Pontif. Acad. Sci. Acta 21, 221-235.
Vorwald-Denholtz, P.P. and De Robertis, E.M. (2011). Temporal pattern of the posterior expression of Wingless in Drosophila blastoderm. Gene Expr. Patterns 11, 456-463.
Ploper, D., Lee, H.X. and De Robertis, E.M. (2011). Dorsal-ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases. Dev. Biol. 352, 317-328.
Taelman, V.F., Dobrowolski, R., Plouhinec, J.L., Fuentealba, L.C., Vorwald, P.P., Gumper, I., Sabatini, D.D. and De Robertis, E.M. (2010). Wnt signaling requires the sequestration of Glycogen Synthase kinase 3 inside Multivesicular Bodies. Cell 143, 1136-1148.
Zakin, L., Chang, E.Y. and De Robertis, E.M. (2010). Crossveinless-2 is required for the relocalization of Chordin protein within the vertebral field in mouse embryos. Dev. Biol. 347, 204-215.
De Robertis, E.M. (2010). Wnt signaling in axial patterning and regeneration: Lessons from Planaria. Sci. Signal. 3, pe21.
Sander, V., Eivers, E., Choi, R.H. and De Robertis, E.M. (2010) Drosophila Smad2 opposes Mad signaling during wing vein development. PLoS ONE 5, e10383.
Tran, U., Zakin, L., Schweickert, A., Agrawal, R., Döger, R., Blum, M., De Robertis, E.M. and Wessely, O. (2010). The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity. Development 137, 1107-1116.
Zakin, L. and De Robertis, E.M. (2010). Extracellular regulation of BMP signaling. Current Biol. 20, R89-R92.
Eivers, E., Demagny, H. and De Robertis, E.M. (2009). Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad. Cytokine Growth F. R. 20, 357-365.
Lee, H.X., Mendes, F.A., Plouhinec, J.L. and De Robertis, E.M. (2009). Enzymatic regulation of pattern: BMP4 binds CUB domains of Tolloids and inhibits proteinase activity. Genes Dev. 23, 2551-2562.
De Robertis, E.M. (2009). Spemann’s organizer and the self-regulation of embryonic fields. Mech. Dev. 126, 925-941.
Fuentealba, L.C., Eivers, E., Lee, H.X. and De Robertis, E.M. (2009). Integration of BMP, RTK, and Wnt signaling through Smad 1 phosphorylations. In: Handbook of Cell Signaling, 2nd edition, R. A. Bradshaw and E. A. Dennis, Eds., Academic Press, Oxford, pages 1989-1994.
Eivers, E., Fuentealba, L.C., Sander, V., Clemens, J., Hartnett, L. and De Robertis, E.M. (2009) Mad is required for Wingless signaling and segment patterning in Drosophila and Xenopus. PLoS ONE 4, e6543.
Plouhinec, J.L. and De Robertis, E.M. (2009). Systems biology of the self-regulating morphogenetic gradient of the Xenopus gastrula. In: Reading and Interpreting Gradients during Development. J. Briscoe, P. Lawrence and J.P. Vincent, Eds., Cold Spring Harb. Perspect. Biol., doi: 10.1101/cshperspect.a001701.
De Robertis, E.M. (2008). Evolutionary Biology Commentary: The molecular ancestry of segmentation mechanisms. Proc. Natl. Acad. Sci. USA 105, 16411-16412.
Zakin, L., Metziner, C.A., Chang, E.Y., Coffinier, C. and De Robertis, E.M. (2008). Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted gastrulation. Dev. Biol.323, 6-18 .
Ambrosio, A.L., Taelman, V.F., Lee, H.X., Metzinger, C.A., Coffinier, C. and De Robertis, E.M. (2008). Crossveinless-2 is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning. Dev. Cell 15, 248-260.
Eivers, E., Fuentealba, L.C. and De Robertis, E.M. (2008). Integrating positional information at the level of Smad1/5/8. Curr. Opin. Genet. Dev. 18, 1-7.
Fuentealba, L.C., Eivers, E., Geissert, D., Taelman, V. and De Robertis, E.M. (2008). Asymmetric mitosis: Unequal segregation of proteins destined for degradation. PNAS 105, 7732-7737.
De Robertis, E.M. (2008). Evo-Devo: Variations on Ancestral themes. Cell 132, 185-195.
Ishibashi, H., Matsumura, N., Hanafusa, H., Matsumoto, K, De Robertis, E.M. and Kuroda, H. (2008). Expression of Siamois and Twin in the blastula chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos. Mech. Dev. 125, 58-66.
Fuentealba, L.C., Eivers, E., Ikeda, A., Hurtado, C., Kuroda, H., Pera, E.M., and De Robertis, E.M. (2007). Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell 131, 980-993.
Yasuda, S., Tanaka, H., Sugiura, H., Okamura, K., Sakaguchi, T., Tran, U., Takemiya, T., Mizoguchi, A., Yagita, Y., Sakurai, T., De Robertis, E.M. and Yamagata, K. (2007). Arcadlin, a synaptic activity-induced protocadherin, regulates dendritic spine number by triggering N-Cadherin endocytosis via TAO2β and p38 MAP kinases. Neuron 56, 456-471.
Hurtado, C. and De Robertis, E.M. (2007). Neural induction in the absence of organizer in salamanders is mediated by Ras/MAPK. Dev. Biol. 307, 282-289.
Plouhinec, J.-L. and De Robertis, E.M. (2007) Systems biology of embryonic morphogens. Molecular BioSystems 3, 454-457.
Sander, V., Reversade, B. and De Robertis, E.M. (2007). The opposing homebox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning. EMBO J. 26, 2955-2965.
Lee, H.X., Ambrosio, A.L., Reversade, B. and De Robertis, E.M. (2006). Embryonic dorsal-ventral signaling: secreted Frizzled-related proteins as inhibitors of Tolloid proteinases. Cell 124, 147-159.
De Robertis, E.M. (2006). Spemann’s organizer and self-regulation in amphibian embryos. Nature Reviews Molecular Cell Biology 7, 296-302.
Publications 2001-2005:
Reversade, B. and De Robertis, E.M. (2005). Formation of a self-differentiating morphogenetic field via reciprocal regulation of Admp and Bmp2/4/7 at opposite poles of the Xenopus embryo. Cell 123, 1147-1160.
Zakin, L., Reversade, B., Kuroda, H., Lyons, K.M. and De Robertis, E.M. (2005). Sirenomelia in Bmp7 and Twisted gastrulation composed mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development 132, 2489-2499.
Kuroda, H., Fuentealba, L., Ikeda, A., Reversade, B. and De Robertis, E.M. (2005). Default neural induction: neuralization of dissociated Xenopus cells is mediated by Ras/MAPK activation. Genes Dev. 19, 1022-1027 .
Wessely, O., Kim, J.I., Tran, U., Fuentealba, L. and De Robertis, E.M. (2005). xBtg-x regulates Wnt/ b -Catenin signaling during early Xenopus development. Dev. Biol. 283, 17-28 .
Reversade, B., Kuroda, H., Lee, H., Mays, A. and De Robertis, E.M. (2005). Depletion of BMP2, 4, 7 and Spemann organizer signals induces massive brain formation in Xenopus embryo. Development 132, 3381-3392.
Pera, E.M., Hou, S., Strate, I., Wessely, O. and De Robertis, E.M. (2005). Exploration of the extracellular space by a large-scale secretion screen in the early Xenopus embryo. Int. J. Dev. Biol. 49, 781-796.
De Robertis, E.M. and Wessely, O. (2004). The molecular nature of Spemann’s organizer. In: The Vertebrate Organizer, H. Grunz, Ed., Springer Verlag, Heidelberg, pp. 55-70.
Oelgeschläger, M., Tran, U., Grubisic, K. and De Robertis, E.M. (2004). Identification of a second Xenopus Twisted gastrulation gene. Int. J. of Dev. Biol. 48, 57-61.
Zakin, L. and De Robertis, E.M. (2004). Inactivation of mouse Twisted gastrulation reveals its role in promoting BMP4 activity during forebrain development. Development 131, 413-424.
De Robertis, E.M. (2004). Goosecoid. In: Gastrulation, C. Stern, Ed., Cold Spring Harbor Laboratory Press, New York, pp. 581-589.
Wessely, O., Kim, J.I., Geissert, D., Tran, U. and De Robertis, E.M. (2004). Analysis of Spemann Organizer formation in Xenopus embryos by cDNA macroarrays. Dev. Biol. 269, 552-566.
Kuroda, H., Wessely, O. and De Robertis, E.M. (2004). Neural induction in Xenopus: requirement for ectodermal and endomesoderm signals via Chordin, Noggin, ß-Catenin and Cerberus. PLoS 2, 623-633.
De Robertis, E.M. and Kuroda, H. (2004). Dorsal-ventral patterning and neural induction in Xenopus embryos. Ann. Rev. Cell & Dev. Biol. Vol. 20, 285-308.
Unterseher, F., Hefele, J.A., Giehl, K., De Robertis, E.M. and Wedlich, D. (2004). Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK. EMBO J. 23, 3259-3269.
Oelgeschläger, M., Kuroda, H., Reversade, B. and De Robertis, E.M. (2003). Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos. Developmental Cell 4, 219-230.
Pera, E.M., Martínez, S.L., Flanagan, J.J., Brechner, M., Wessely, O. and De Robertis, E.M. (2003). Darmin is a novel secreted protein expressed during endoderm development in Xenopus. Gene Exp. Patterns, Mech. Dev. 3, 147-152.
Bachiller, D., Klingensmith, J., Schneyder, N., Tran, U., Anderson, R., Rossant, J. and De Robertis, E.M. (2003). The role of Chordin/BMP signals in mammalian pharyngeal development and DiGeorge syndrome. Development 130, 3567-3578.
Oelgeschläger, M., Reversade, B., Larraín, J., Little, S., Mullins, M.C. and De Robertis, E.M. (2003). The pro-BMP activity of Twisted gastrulation is independent of BMP binding. Development 130, 4047-4056.
Larraín, J., Brown, C. and De Robertis, E.M. (2003). Integrin-a3 mediates binding of Chordin to the cell surface and promotes its endocytosis. EMBO reports 4, 813-818.
Pera, E.M., Ikeda, A., Eivers, E. and De Robertis, E.M. (2003). Integration of IGF, FGF and anti-BMP signals via Smad1 phosphorylation in neural induction. Genes Dev. 17, 3023-3028.
Abreu, J.G., Coffinier, C., Larraín, J., Oelgeschläger, M. and De Robertis, E.M. (2002). Chordin-like CR domains and the regulation of evolutionarily conserved extracellular signaling systems. Gene 287, 39-47.
Wessely, O. and De Robertis, E.M. (2002). Neural plate patterning by secreted signals. Neuron 33, 489-491.
Pera, E.M., Kim, J.I., Martínez, S.L., Brechner, M., Li, S.Y., Wessely, O. and De Robertis, E.M. (2002). Isthmin is a novel secreted protein expressed as part of the Fgf-8 synexpression group in the Xenopus midbrain-hindbrain organizer. Mech. Dev. 116, 169-2002.
Abreu, J.G., Ketpura, N.I., Reversade, B. and De Robertis, E.M. (2002). Connective tissue growth factor modulates cell signalling by BMP and TGF-ß. Nature Cell Biology 4, 599-604.
Coffinier, C., Ketpura, N., Tran, U., Geissert, D. and De Robertis, E.M. (2002). Mouse Crossveinless-2 as the vertebrate homolog of a Drosophila extracellular receptor of BMP signaling. Gene Exp. Patterns, Mech. Dev. 2, 189-194.
Coffinier, C., Tran, U., Larraín, J. and De Robertis, E.M. (2001). Neuralin is a novel Chordin-related molecule expressed in the mouse neural plate. Mech. Dev. 100, 119-122.
Brizuela, B.J., Wessely, O. and De Robertis, E.M. (2001). Overexpression of the Xenopus Claudin tight junction protein causes randomization of the left-right body axis. Developmental Biology 230, 217-229.
Wessely, O., Tran, U., Zakin, L. and De Robertis, E.M. (2001). Identification and expression of the mammalian homologue of Bicaudal-C. Mech. Dev. 101, 267-270.
De Robertis, E.M., Wessely, O., Oelgeschläger, M., Brizuela, B., Pera, E., Larraín, J., Abreu, J. and Bachiller, D. (2001). Molecular mechanisms of cell-cell signalling by Spemann’s organizer. Int. J. Dev. Biol. 45, 189-197. Preface to IJDB issue.
Wessely, O., Agius, E., Oelgeschläger, M., Pera, E.M. and De Robertis, E.M. (2001). Neural induction in the absence of mesoderm: -catenin dependent expression of secreted BMP antagonists at the blastula stage in Xenopus. Dev. Biol. 234, 161-173.
De Robertis, E.M. and Bouwmeester, T. (2001). New twists on embryonic patterning. EMBO Reports 21, 661-665.
Larraín, J., Oelgeschläger, M., Ketpura, N.I., Reversade, B., Zakin, L. and De Robertis, E.M. (2001). Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation on BMP. Development 128, 4439-4447.
Pera, E.M., Wessely, O., Li, S.Y. and De Robertis, E.M. (2001). Neural and head induction by Insulin-like Growth Factor signals. Developmental Cell 1, 655-665.
Publications 2000-1996:
Larraín, J., Bachiller, D., Lu, B., Agius, E., Piccolo, S. and De Robertis, E.M. (2000). BMP-binding modules in Chordin: a model for signalling regulation in the extracellular space. Development 127, 821-830.
Agius, E., Oelgeschläger, M., Wessely, O. and De Robertis, E.M. (2000). Endodermal Nodal-related signals and mesoderm induction in Xenopus. Development 127, 1173-1183.
Bachiller, D., Klingensmith, J., Kemp, C., Belo, J.A., Anderson, R.M., May, S.R., McMahon, J.A., McMahon, A.P., Harland, R., Rossant, J. and De Robertis, E.M. (2000). The organizer secreted factors Chordin and Noggin are required for forebrain development in the mouse. Nature 403, 658-661.
Belo, J.A., Bachiller, D., Agius, E., Kemp, C., Borges, A.C., Marques, S., Piccolo, S. and De Robertis, E. M. (2000). Cerberus-like is a secreted BMP and Nodal antagonist not essential for mouse development. Genesis 26, 265-270.
Wessely, O. and De Robertis, E.M. (2000). The Xenopus homologue of Bicaudal-C is a localized maternal mRNA that regulates endoderm development. Development 127, 2053-2062.
Yamamoto, A., Kemp, C., Bachiller, D., Geissert, D. and De Robertis, E.M. (2000). Mouse paraxial protocadherin is expressed in trunk mesoderm and is not essential for mouse development. Genesis 27, 49-57.
Oelgeschläger, M., Larraín, J., Geissert, D. and De Robertis, E.M. (2000). The evolutionary conserved BMP-binding protein Twisted Gastrulation promotes BMP signalling. Nature 405, 757-763.
Pera, E. and De Robertis, E.M. (2000). A direct screen for secreted proteins in Xenopus embryos identifies distinct activities for the Wnt antagonists Crescent and Frzb-1. Mech. Dev. 96, 197-207.
Kim, S.H., Jen, W.C., De Robertis, E.M. and Kintner, C. (2000). The protocadherin PAPC establishes segmental boundaries during somitogenesis in Xenopus embryos. Curr. Biol. 10, 821-830.
De Robertis, E.M., Larraín, J., Oelgeschläger, M. and Wessely, O. (2000). The establishment of Spemann’s Organizer and patterning of the vertebrate embryo. Nature Reviews Genetics 1, 171-181.
Piccolo, S., Agius, E., Leyns, L., Battacharyya, S., Grunz, H., Bouwmeester, T. and De Robertis, E.M. (1999). The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals. Nature 397, 707-710.
Borello, U., Coletta, M., Tajbakhsh, S., Leyns, L., De Robertis, E.M., Buckingham, M. and Cossu, G. (1999). Transplacental delivery of the Wnt antagonist Frzb1 inhibits development of caudal paraxial mesoderm and skeletal myogenesis in mouse embryos. Development 126, 4247-4255.
Agius, E., Piccolo, S. and De Robertis, E.M. (1999). Etudes épistatiques démontrant que l’inducteur cépalique Cerberus est un inhibiteur multivalent fonctionnant exclusivement dans l’espace extracellulaire. Journal de la Société de Biologie, Vol. 193 , 347-354.
Duprez, D., Leyns, L., Bonnin, M.A., Lapointe, F., Etchevers, H., De Robertis, E.M. and Le Douarin, N. (1999). Expression of Frzb-1 during chick development. Mech. Dev. 89, 179-183
Zhu, L., Belo, J.A., De Robertis, E.M. and Stern, C.D. (1999). Goosecoid regulates the neural inducing strength of the mouse node. Dev. Biol. 216, 276-281.
De Robertis, E.M. (1999). A nose for the embryo: the work of Pieter Nieuwkoop. Int. J. Dev. Biol.43, 603-604.
Konishi, Y., Tominaga, M., Watanabe, Y., Imamura, F., Goldfarb, A., Maki, R., Blum, M., De Robertis, E.M. and Tominaga, A. (1999). Goosecoid inhibits erythrocyte differentiation by competing with Rb for PU.1 binding in murine cells. Oncogene 18, 6795-6805.
Pillemer, G., Epstein, M., Blumberg, B., Yisraeli, J.K., De Robertis, E.M., Steinbeisser, H. and Fainsod, A. (1998). Nested expression and sequential downregulation of the Xenopus caudal genes along the anterior-posterior axis. Mech. Dev. 71, 193-196.
Belo, J.A., Leyns, L., Yamada, G. and De Robertis, E.M. (1998). The prechordal midline of the chondrocranium is defective in Goosecoid-1 mouse mutants. Mech. Dev.72, 15-26.
Blumberg, B., Kang, H., Bolado, J., Chen, H., Craig, A.G., Moreno, T.A., Umesono, K., Perlmann, T., De Robertis, E.M. and Evans, R.M. (1998). BXR, an embryonic orphan nuclear receptor activated by a novel class of endogenous benzoate metabolites. Genes Dev. 12, 1269-1277.
Yamamoto, A., Amacher, S.L., Kim, S.H., Geissert, D., Kimmel, C.B. and De Robertis, E.M. (1998). Zebrafish paraxial protocadherin is a downstream target of spadetail involved in morphogenesis of gastrula mesoderm. Development 125, 3389-3397.
Kim, S.H., Yamamoto, A., Bouwmeester, T., Agius, E. and De Robertis, E.M. (1998). The role of paraxial protocadherin in selective adhesion and cell movements of the mesodermal mantle during Xenopus gastrulation. Development 125, 4681-4691.
Leyns, L., Bouwmeester, T., Kim, S., Piccolo, S. and De Robertis, E.M. (1997). Frzb-1 is a secreted antagonist of Wnt signalling expressed in the Spemann’s organiser. Cell 88, 747-756
De Robertis, E.M. (1997). The ancestry of segmentation. Nature387, 25-26
Piccolo, S., Agius, E., Lu, B., Goodman, S., Dale, L., and De Robertis, E.M. (1997) Cleavage of chordin by Xolloid Metalloprotease suggest a role for proteolytic processing in the regulation of Spemann organizer activity. Cell 91, 407-416.
Belo, J.A., Bouwmeester, T.,Leyns, L.,Kertesz, N., Gallo, M., Folletie, M. and De Robertis, E.M. (1997). Cerberus-like is a secreted factor with neuralizing activity expressed in the anterior primitive endoderm of the mouse gastrula. Mech. Dev. 68, 45-57.
Pfeffer, P.L., De Robertis, E.M. and Izpisúa-Belmonte, J.C. (1997). Crescent, a novel chick gene encoding a frizzled-like cysteine-rich domain, is expressed in anterior regions during early embryogenesis. Int. J. Dev. Biol. 41, 449-458.
Heanue, T.A., Johnson, R.L., Izpisúa-Belmonte, J.C., Stern, C.D., De Robertis, E.M. and Tabin, C.J. (1997) Goosecoid misexpression alters the morphology and Hox gene expression of the developing chick limb buds. Mech. Dev. 69, 31-37.
De Robertis, E.M., Kim. S.H., Leyns, L., Piccolo, S., Bachiller, D., Agius, E., Belo, J.A., Yamamoto, A., Hainski-Brosseau, A., Brizuela, B., Wessely, O., Lu, B. and Bouwmeester, T. (1997). Patterning by genes expressed in Spemann’s organizer. Cold Spring Harbor Symp. Quant. Biol. 62, 169-175.
Bouwmeester, T., Kim, S., Sasai, Y., Lu, B. and De Robertis, E.M. (1996). Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann’s Organizer. Nature 382, 595-601
Catala, M., Teillet, M.A., De Robertis, E.M. and Le Douarin, N.M. (1996). A spinal cord fate map in the avian embryo: while regressing, the Hensen’s node lays down the floor plate and notochord thus joining the spinal cord lateral walls. Development 122, 2599-2610
De Robertis, E.M. and Sasai, Y. (1996). A common plan for dorso-ventral patterning in Bilateria. Nature 380, 37-40.
Gont, L.K., Fainsod, A., Kim, S. and De Robertis, E.M. (1996). Overexpression of the homeobox gene Xnot-2 leads to notochord formation in Xenopus. Developmental Biology, 174,174-178
Holley, S.A., Neul, J.L., Attisano, L., Wrana, J.L., Sasai, Y., O’Connor, M.B., De Robertis, E.M. and Ferguson, E.L. (1996). The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by blocking dpp signaling upstream of receptor activation. Cell 86, 607-617.
Piccolo, S., Sasai, Y., Lu, B. and De Robertis, E.M. (1996). Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of Chordin to BMP-4. Cell 86, 589-598
Sasai, Y., Lu, B., Piccolo, S. and De Robertis, E. (1996). Endoderm induction by the organizer secreted factors Chordin and Noggin in Xenopus animal caps. The EMBO J. 15, 4547-4555.
Publications 1995-1991:
De Robertis, E.M. (1995). Dismantling the organizer. Nature 374, 407-408.
Yamada, G., Mansouri, A., Torres, M., Stuart, E.T., Blum, M., Schultz, M., De Robertis, E.M., and Gruss, P. (1995). Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death. Development 121, 2917-2922.
Holley, S.A., Jackson, P. D., Sasai, Y., Lu, B., De Robertis, E M., Hoffmann, F.M., and Ferguson, E.L. (1995). A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin. Nature 376, 249-253.
Sasai, Y., Lu, B., Steinbeisser, H., and De Robertis, E.M. (1995). Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature 376, 333-336.
Steinbeisser, H., Fainsod, A., Niehrs, C., Sasai, Y., and De Robertis, E.M. (1995). The role of gsc and BMP-4 in dorsal-ventral patterning of the marginal zone in Xenopus: a loss-of-function study using antisense RNA. Embo J. 14, 5230-5243.
Blum, M., De Robertis, E.M., Kojis, T., Heinzmann, C., Klisak, I., Geissert, D., and Sparkes, R.S. (1994). Molecular cloning of the human homeobox gene goosecoid (GSC) and mapping of the gene to human chromosome 14q32.1. Genomics 21, 388-393.
Niehrs, C., Steinbeisser, H., and De Robertis, E.M. (1994). Mesodermal patterning by a gradient of the vertebrate homeobox gene goosecoid. Science 263, 817-820.
Fainsod, A., Steinbeisser, H., and De Robertis, E.M. (1994). On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo. Embo J. 13, 5015-5025.
Schulte-Merker, S., Hammerschmidt, M., Beuchle, D., Cho, K.W., De Robertis, E.M., and Nusslein-Volhard, C. (1994). Expression of zebrafish goosecoid and no tail gene products in wild- type and mutant no tail embryos. Development 120, 843-852.
De Robertis, E.M., Fainsod, A., Gont, L.K., and Steinbeisser, H. (1994). The evolution of vertebrate gastrulation. Dev. Suppl., 117-124.
Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L. K., and De Robertis, E.M. (1994). Xenopus chordin: a novel dorsalizing factor activated by organizer- specific homeobox genes. Cell 79, 779-790.
Pfeffer, P.L., and De Robertis, E.M. (1994). Regional specificity of RAR gamma isoforms in Xenopus development. Mech. Dev. 45, 147-53.
Steinbeisser, H., and De Robertis, E.M. (1993). Xenopus goosecoid: a gene expressed in the prechordal plate that has dorsalizing activity. C. R. Acad. Sc., Parisi 316, 959-971.
Steinbeisser, H., De Robertis, E.M., Ku, M., Kessler, D.S., and Melton, D.A. (1993). Xenopus axis formation: induction of goosecoid by injected Xwnt-8 and activin mRNAs. Development 118, 499-507.
Bittner, D., De Robertis, E M., and Cho, K.W. (1993). Characterization of the Xenopus Hox 2.4 gene and identification of control elements in its intron. Dev. Dy.n 196, 11-24.
Izpisua-Belmonte, J.C., De Robertis, E.M., Storey, K.G., and Stern, C.D. (1993). The homeobox gene goosecoid and the origin of organizer cells in the early chick blastoderm. Cell 74, 645-59.
Gaunt, S.J., Blum, M., and De Robertis, E.M. (1993). Expression of the mouse goosecoid gene during mid-embryogenesis may mark mesenchymal cell lineages in the developing head, limbs and body wall. Development 117, 769-78.
Niehrs, C., Keller, R., Cho, K.W., and De Robertis, E.M. (1993). The homeobox gene goosecoid controls cell migration in Xenopus embryos. Cell 72, 491-503.
Gont, L.K., Steinbeisser, H., Blumberg, B., and de Robertis, E.M. (1993). Tail formation as a continuation of gastrulation: the multiple cell populations of the Xenopus tailbud derive from the late blastopore lip. Development 119, 991-1004.
Jones, F.S., Holst, B.D., Minowa, O., De Robertis, E.M., and Edelman, G.M. (1993). Binding and transcriptional activation of the promoter for the neural cell adhesion molecule by HoxC6 (Hox-3.3). Proc. Nat.l Acad. Sci. USA 90, 6557-61.
Storey, K.G., Crossley, J.M., De Robertis, E.M., Norris, W.E., and Stern, C.D. (1992). Neural induction and regionalisation in the chick embryo. Development 114, 729-741.
Blum, M., Gaunt, S.J., Cho, K.W., Steinbeisser, H., Blumberg, B., Bittner, D., and De Robertis, E.M. (1992). Gastrulation in the mouse: the role of the homeobox gene goosecoid. Cell 69, 1097-1106.
Jegalian, B.G., Miller, R.W., Wright, C.V., Blum, M., and De Robertis, E.M. (1992). A Hox 3.3-lacZ transgene expressed in developing limbs. Mech. Dev. 39, 171-180.
Jegalian, B.G., and De Robertis, E.M. (1992). Homeotic transformations in the mouse induced by overexpression of a human Hox3.3 transgene. Cell 71, 901-910.
Blumberg, B., Mangelsdorf, D.J., Dyck, J.A., Bittner, D.A., Evans, R.M., and De Robertis, E.M. (1992). Multiple retinoid-responsive receptors in a single cell: families of retinoid “X” receptors and retinoic acid receptors in the Xenopus egg. Proc. Natl. Acad. Sc. USA 89, 2321-2325.
Leroy, P., and De Robertis, E.M. (1992). Effects of lithium chloride and retinoic acid on the expression of genes from the Xenopus laevis Hox 2 complex. Dev. Dyn. 194, 21-32.
Niehrs, C., and De Robertis, E.M. (1992). Vertebrate axis formation. Curr. Opin. Genet. Dev. 2, 550-555.
Jones, F.S., Prediger, E.A., Bittner, D.A., De Robertis, E.M., and Edelman, G.M. (1992). Cell adhesion molecules as targets for Hox genes: neural cell adhesion molecule promoter activity is modulated by cotransfection with Hox-2.5 and -2.4. Proc. Natl. Acad. Sc.i USA 89, 2086-2090.
Blumberg, B., Wright, C.V., De Robertis, E.M., and Cho, K.W. (1991). Organizer-specific homeobox genes in Xenopus laevis embryos. Science 253, 194-196.
Niehrs, C., and De Robertis, E.M. (1991). Ectopic expression of a homeobox gene changes cell fate in Xenopus embryos in a position-specific manner. Embo J. 10, 3621-3629.
De Robertis, E.M., Morita, E.A., and Cho, K.W. (1991). Gradient fields and homeobox genes. Development 112, 669-78.
Cho, K.W., Morita, E.A., Wright, CV., and De Robertis, E.M. (1991). Overexpression of a homeodomain protein confers axis-forming activity to uncommitted Xenopus embryonic cells. Cell 65, 55-64.
Cho, K.W., Blumberg, B., Steinbeisser, H., and De Robertis, E.M. (1991). Molecular nature of Spemann’s organizer: the role of the Xenopus homeobox gene goosecoid. Cell 67, 1111-1120.
Publications 1990-1986:
De Robertis, E.M., Oliver, G., and Wright, C.V. (1990). Homeobox genes and the vertebrate body plan. Sc. Am. 263, 46-52.
Chuong, C.M., Oliver, G., Ting, S.A., Jegalian, B G., Chen, H.M., and De Robertis, E.M. (1990). Gradients of homeoproteins in developing feather buds. Development 110, 1021-1030.
Wright, C.V., Morita, E.A., Wilkin, D.J., and De Robertis, E.M. (1990). The Xenopus XIHbox 6 homeo protein, a marker of posterior neural induction, is expressed in proliferating neurons. Development 109, 225-234.
Molven, A., Wright, C.V., Bremiller, R., De Robertis, E.M., and Kimmel, C.B. (1990). Expression of a homeobox gene product in normal and mutant zebrafish embryos: evolution of the tetrapod body plan. Development 109, 279-288.
Oliver, G., De Robertis, E.M., Wolpert, L., and Tickle, C. (1990). Expression of a homeobox gene in the chick wing bud following application of retinoic acid and grafts of polarizing region tissue. Embo J. 9, 3093-3099.
Jegalian, B.G., and De Robertis, E.M. (1990). The Xenopus laevis Hox 2.1 homeodomain protein is expressed in a narrow band of the hindbrain. Int. J. Dev. Biol. 34, 453-456.
Livingston, B.D., De Robertis, E.M., and Paulson, J.C. (1990). Expression of beta-galactoside alpha 2,6 sialyltransferase blocks synthesis of polysialic acid in Xenopus embryos. Glycobiology 1, 39-44.
Cho, K.W., and De Robertis, E.M. (1990). Differential activation of Xenopus homeo box genes by mesoderm-inducing growth factors and retinoic acid. Genes Dev. 4, 1910-1916.
Wright, C. V., Schnegelsberg, P., and De Robertis, E.M. (1989). XlHbox 8: a novel Xenopus homeo protein restricted to a narrow band of endoderm. Development 105, 787-794.
De Robertis, E.M., Oliver, G., and Wright, C.V. (1989). Determination of axial polarity in the vertebrate embryo: homeodomain proteins and homeogenetic induction. Cell 57, 189-191.
Wright, C.V., Cho, K.W., Hardwicke, J., Collins, R.H., and De Robertis, E.M. (1989). Interference with function of a homeobox gene in Xenopus embryos produces malformations of the anterior spinal cord. Cell 59, 81-93.
Fritz, A.F., Cho, K.W., Wright, C.V., Jegalian, B.G., and De Robertis, E.M. (1989). Duplicated homeobox genes in Xenopus. Dev. Biol. 131, 584-588.
Oliver, G., Sidell, N., Fiske, W., Heinzmann, C., Mohandas, T., Sparkes, R.S., and De Robertis, E.M. (1989). Complementary homeo protein gradients in developing limb buds. Genes Dev. 3, 641-650.
Wright, C. V., Cho, K. W., Oliver, G., and De Robertis, E. M. (1989). Vertebrate homeodomain proteins: families of region-specific transcription factors. Trends Biochem Sci 14, 52-6.
Cho, K.W., Goetz, J., Wright, C.V., Fritz, A., Hardwicke, J., and De Robertis, E.M. (1988). Differential utilization of the same reading frame in a Xenopus homeobox gene encodes two related proteins sharing the same DNA-binding specificity. Embo J. 7, 2139-2149.
Oliver, G., Wright, C.V., Hardwicke, J., and De Robertis, E.M. (1988). Differential antero-posterior expression of two proteins encoded by a homeobox gene in Xenopus and mouse embryos. Embo J. 7, 3199-3209.
Oliver, G., Wright, C.V., Hardwicke, J., and De Robertis, E.M. (1988). A gradient of homeodomain protein in developing forelimbs of Xenopus and mouse embryos. Cell 55, 1017-1024.
De Robertis, E.M., Burglin, T.R., Fritz, A., Oliver, G., Cho, K., and Wright, C.V. (1988). Sequence conservations in vertebrate homeo-box mRNAs. Arc. Biol. Med. Exp. 21, 443-447.
Fritz, A., and De Robertis, E.M. (1988). Xenopus homeobox-containing cDNAs expressed in early development. Nucleic Acids Res. 16, 1453-1469.
Fritz, A.F., Martin, G., Wright, C.V., and De Robertis, E.M. (1988). Site-specific inversions in repeated Xenopus laevis homeobox gene 2 sequences. Nucleic Acids Res. 16, 9058.
Sharpe, C.R., Fritz, A., De Robertis, E.M., and Gurdon, J.B. (1987). A homeobox-containing marker of posterior neural differentiation shows the importance of predetermination in neural induction. Cell 50, 749-758.
Mattaj, I.W., Coppard, N J., Brown, R.S., Clark, B.F., and De Robertis, E.M. (1987). 42S p48–the most abundant protein in previtellogenic Xenopus oocytes– resembles elongation factor 1 alpha structurally and functionally. Embo J. 6, 2409-2413.
Wright, C.V., Cho, K.W., Fritz, A., Burglin, T.R., and De Robertis, E.M. (1987). A Xenopus laevis gene encodes both homeobox-containing and homeobox- less transcripts. Embo J. 6, 4083-4094.
Burglin, T.R., and De Robertis, E.M. (1987). The nuclear migration signal of Xenopus laevis nucleoplasmin. Embo J. 6, 2617-2625.
Burglin, T.R., Mattaj, I.W., Newmeyer, D.D., Zeller, R., and De Robertis, E.M. (1987). Cloning of nucleoplasmin from Xenopus laevis oocytes and analysis of its developmental expression. Genes Dev. 1, 97-107.
Burglin, T. R., Wright, C. V., and De Robertis, E. M. (1987). Translational control in homoeobox mRNAs? [letter]. Nature 330, 701-702.
Newmeyer, D.D., Lucocq, J.M., Burglin, T.R., and De Robertis, E.M. (1986). Assembly in vitro of nuclei active in nuclear protein transport: ATP is required for nucleoplasmin accumulation. Embo J. 5, 501-510.
Mattaj, I.W., Lienhard, S., Jiricny, J., and De Robertis, E.M. (1985). An enhancer-like sequence within the Xenopus U2 gene
promoter facilitates the formation of stable transcription complexes.
Nature 316, 163-167.
Mattaj, I.W., and De Robertis, E.M. (1985). Nuclear segregation
of U2 snRNA requires binding of specific snRNP proteins. Cell
40, 111-118.
Mattaj, I.W., Zeller, R., Carrasco, A.E., Jamrich, M., Lienhard,
S., and De Robertis, E.M. (1985). U snRNA gene families in Xenopus
laevis. Oxf, Surv, Eukaryot, Genes 2, 121-140.